HitPredict

Interactor 1: DLG4 (P31016)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: DLGP2 (P97837)
Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2)
Gene: Dlgap2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	9115257
Identification Methods	two hybrid, protein array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030425 - dendrite GO:0043197 - dendritic spine GO:0045211 - postsynaptic membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Rn			1 1059
+	Mm
		1143394 DLG4_MOUSE (1-724): 0: 676: 99.45		DLGP2_MOUSE (1-1059): 0: 1482: 97.55
+	Hs
		942392 DLG4_HUMAN (1-724): 0: 676: 99.86		DLGP2_HUMAN (1-1059): 0: 1460: 88.95
+	Rn
		957001 DLG3_RAT (9-724): 0: 595: 62.80		DLGP2_RAT (1-1059): 0: 1476: 100.00
+	Hs
		1271035 DLG3_HUMAN (28-724): 0: 603: 64.37		DLGP2_HUMAN (1-1059): 0: 1460: 88.95
+	Hs
		4619 DLG3_HUMAN (28-724): 0: 603: 64.37		A0A1B0GTN4_HUMAN (5-1059): 0: 1450: 88.82
+	Hs
		145945 DLG4_HUMAN (1-724): 0: 676: 99.86		DLGP1_HUMAN (80-1059): 0: 1134: 50.98
+	Rn
		677775 DLG4_RAT (1-724): 0: 677: 100.00		DLGP1_RAT (80-1059): 0: 1113: 50.24
+	Mm
		1143504 DLG4_MOUSE (1-724): 0: 676: 99.45		DLGP1_MOUSE (80-1059): 0: 1109: 50.24
+	Hs
		145952 DLG3_HUMAN (28-724): 0: 603: 64.37		DLGP1_HUMAN (80-1059): 0: 1134: 50.98
+	Hs
		327234 DLG4_HUMAN (1-724): 0: 676: 99.86		DLGP3_HUMAN (80-1059): 0: 1038: 44.85
+	Rn
		956990 DLG3_RAT (9-724): 0: 595: 62.80		DLGP1_RAT (80-1059): 0: 1113: 50.24
+	Rn
		677777 DLG4_RAT (1-724): 0: 677: 100.00		DLGP3_RAT (80-1059): 0: 1012: 43.95
+	Mm
		1143344 DLG4_MOUSE (1-724): 0: 676: 99.45		DLGP3_MOUSE (80-1059): 0: 1012: 44.33
+	Rn
		957006 DLG3_RAT (9-724): 0: 595: 62.80		DLGP3_RAT (80-1059): 0: 1012: 43.95
+	Hs
		942402 DLG4_HUMAN (1-724): 0: 676: 99.86		DLGP4_HUMAN (80-1059): 0: 930: 41.09
+	Mm
		69918 DLG4_MOUSE (1-724): 0: 676: 99.45		DLGP4_MOUSE (80-1059): 0: 903: 41.09
+	Rn
		677778 DLG4_RAT (1-724): 0: 677: 100.00		DLGP4_RAT (80-1059): 0: 882: 40.56
+	Hs
		1271042 DLG3_HUMAN (28-724): 0: 603: 64.37		DLGP4_HUMAN (80-1059): 0: 930: 41.09
+	Hs
		1153634 DLG3_HUMAN (28-724): 0: 603: 64.37		Q6IS01_HUMAN (80-611): 0: 677: 50.36
+	Mm
		1143445 DLG4_MOUSE (1-724): 0: 676: 99.45		DLGP5_MOUSE (454-1055): 7.42e-175: 533: 18.06