HitPredict

Interactor 1: DLG4 (P31016)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: NMDE1 (Q00959)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A)
Gene: Grin2a

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.740

The method score is based on:

Property Details
Experiments 20847060, 28823933, 17670980, 8601796, 10336672, 11222640, 7569905
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, pull down, filter binding
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
and 21 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 724
Rn

1 1464
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024