HitPredict - High confidence protein-protein interactions

Interactor 1: DLG4 (P31016)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: DLG1 (Q62696)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97)
Gene: DLG1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	16332687, 21119615
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Guanylate_kin~Guanylate_kin, Guanylate_kin~PDZ, Guanylate_kin~SH3_1, PDZ~PDZ, SH3_1~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005911 - cell-cell junction and 21 others more... GO:0007268 - chemical synaptic transmission GO:0014069 - postsynaptic density GO:0016323 - basolateral plasma membrane GO:0019894 - kinesin binding GO:0019901 - protein kinase binding GO:0021987 - cerebral cortex development GO:0030054 - cell junction GO:0030165 - PDZ domain binding GO:0030425 - dendrite GO:0031594 - neuromuscular junction GO:0035255 - ionotropic glutamate receptor binding GO:0043005 - neuron projection GO:0045197 - establishment or maintenance of epithelial cell apical/basal polarity GO:0045202 - synapse GO:0045211 - postsynaptic membrane GO:0097060 - synaptic membrane GO:0098609 - cell-cell adhesion GO:0098839 - postsynaptic density membrane GO:0098919 - structural constituent of postsynaptic density GO:0098978 - glutamatergic synapse GO:0099645 - neurotransmitter receptor localization to postsynaptic specialization membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	724
Rn

1	911

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024