HitPredict

Interactor 1: DLG4 (P31016)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: TANC1 (Q6F6B3)
Protein TANC1 (TPR domain, ankyrin-repeat and coiled-coil domain-containing protein 1)
Gene: TANC1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15673434
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0030425 - dendrite GO:0098978 - glutamatergic synapse
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 724 Rn			1 1849
+	Mm
		1012698 DLG4_MOUSE (1-724): 0: 676: 99.45		TANC1_MOUSE (1-1849): 0: 1741: 95.10
+	Hs
		942379 DLG4_HUMAN (1-724): 0: 676: 99.86		TANC1_HUMAN (1-1849): 0: 1704: 87.75
+	Rn
		1144016 DLG1_RAT (5-724): 0: 565: 69.13		TANC1_RAT (1-1849): 0: 1752: 100.00
+	Hs
		1021559 DLG1_HUMAN (28-724): 0: 580: 72.65		TANC1_HUMAN (1-1849): 0: 1704: 87.75
+	Hs
		1050051 SCRIB_HUMAN (58-243): 6.07e-25: 113: 40.72		TANC1_HUMAN (1-1849): 0: 1704: 87.75
+	Mm
		103602 DLG4_MOUSE (1-724): 0: 676: 99.45		ANK3_MOUSE (895-1538): 8.16e-93: 337: 19.82
+	Mm
		56844 DLG4_MOUSE (1-724): 0: 676: 99.45		TANC2_MOUSE (797-1849): 8.02e-67: 253: 15.78
+	Dm
		677703 DLG1_DROME (22-322): 2.17e-26: 117: 19.21		Q8WS23_DROME (356-1427): 0: 734: 41.94
+	Hs
		1050092 SCRIB_HUMAN (58-243): 6.07e-25: 113: 40.72		ANR50_HUMAN (375-1750): 0: 677: 20.40
+	Mm
		1143380 DLG4_MOUSE (1-724): 0: 676: 99.45		DAPK1_MOUSE (1127-1238): 3.86e-11: 70.9: 34.82
+	Mm
		1143421 DLG4_MOUSE (1-724): 0: 676: 99.45		ANK2_MOUSE (1278-1849): 1.01e-09: 66.2: 8.19
+	Hs
		1021434 DLG5_HUMAN (40-245): 4.68e-17: 88.2: 32.54		ANK3_HUMAN (895-1538): 1.75e-88: 325: 19.68
+	Dm
		677732 DLG1_DROME (22-322): 2.17e-26: 117: 19.21		Q9W2I0_DROME (1002-1238): 5.89e-21: 102: 32.23