HitPredict

Interactor 1: SNC1 (P31109)
Synaptobrevin homolog 1
Gene: SNC1

Interactor 2: SEC17 (P32602)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha) (Vesicular-fusion protein SEC17) (alpha-SNAP chaperone)
Gene: SEC17

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	9195974, 17522384
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0019905 - syntaxin binding GO:0031201 - SNARE complex GO:0048280 - vesicle fusion with Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Sc			1 292
+	Zm
		31296 A0A1D6KH00_MAIZE (2-114): 4.55e-44: 153: 24.78		A0A1D6PZ82_MAIZE (2-269): 6.86e-90: 272: 29.85
+	Dm
		1095560 Q7JYX5_DROME (2-115): 1.97e-34: 120: 22.81		SNAP_DROME (3-289): 9.54e-100: 295: 32.40
+	Dm
		577215 SYB_DROME (16-111): 8.59e-31: 108: 30.21		SNAP_DROME (3-289): 9.54e-100: 295: 32.40
+	Hs
		850546 VAMP7_HUMAN (2-116): 6.23e-28: 103: 31.30		SNAA_HUMAN (12-291): 5.14e-101: 299: 35.00
+	Hs
		261720 VAMP4_HUMAN (24-96): 3.73e-24: 91.5: 31.51		SNAB_HUMAN (3-289): 1.36e-101: 300: 33.80
+	Hs
		261646 VAMP4_HUMAN (24-96): 3.73e-24: 91.5: 31.51		SNAA_HUMAN (12-291): 5.14e-101: 299: 35.00
+	Mm
		659546 VAMP2_MOUSE (22-98): 7.29e-24: 90: 37.66		SNAB_MOUSE (3-289): 1.36e-101: 300: 33.80
+	Hs
		873528 VAMP2_HUMAN (22-98): 7.29e-24: 90: 37.66		SNAA_HUMAN (12-291): 5.14e-101: 299: 35.00
+	Dm
		115802 M9PGI6_DROME (4-106): 3.27e-24: 93.4: 24.07		SNAP_DROME (3-289): 9.54e-100: 295: 32.40
+	Hs
		873545 VAMP3_HUMAN (25-95): 8.07e-24: 89.2: 35.21		SNAA_HUMAN (12-291): 5.14e-101: 299: 35.00
+	Sc
		605825 SEC22_YEAST (8-109): 2.67e-24: 93.8: 17.59		SEC17_YEAST (1-292): 5.94e-97: 288: 100.00
+	Hs
		850592 VAMP7_HUMAN (2-116): 6.23e-28: 103: 31.30		SNAG_HUMAN (1-248): 1.09e-67: 214: 21.20
+	Dm
		1178116 Q7JYX5_DROME (2-115): 1.97e-34: 120: 22.81		Q9U6R9_DROME (1-262): 1.1e-59: 194: 21.29
+	Hs
		261710 VAMP4_HUMAN (24-96): 3.73e-24: 91.5: 31.51		SNAG_HUMAN (1-248): 1.09e-67: 214: 21.20
+	Dm
		1178122 Q7JYX5_DROME (2-115): 1.97e-34: 120: 22.81		Q9VH25_DROME (23-262): 3.76e-56: 184: 21.49
+	Hs
		926249 VAMP2_HUMAN (22-98): 7.29e-24: 90: 37.66		SNAG_HUMAN (1-248): 1.09e-67: 214: 21.20
+	Hs
		1079416 VAMP3_HUMAN (25-95): 8.07e-24: 89.2: 35.21		SNAG_HUMAN (1-248): 1.09e-67: 214: 21.20
+	Dm
		577238 SYB_DROME (16-111): 8.59e-31: 108: 30.21		Q9U6R9_DROME (1-262): 1.1e-59: 194: 21.29
+	Dm
		115822 M9PGI6_DROME (4-106): 3.27e-24: 93.4: 24.07		Q9U6R9_DROME (1-262): 1.1e-59: 194: 21.29
+	Dm
		115828 M9PGI6_DROME (4-106): 3.27e-24: 93.4: 24.07		Q9VH25_DROME (23-262): 3.76e-56: 184: 21.49