HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: RAB14 (P61106)
Ras-related protein Rab-14 (EC 3.6.5.2)
Gene: RAB14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.909

Property	Details
Experiments	26496610, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 215
+	Hs
		678338 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2A_HUMAN (8-195): 6.73e-96: 280: 62.77
+	Hs
		591751 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77
+	Hs
		678344 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1A_HUMAN (1-215): 1.44e-87: 258: 42.33
+	Hs
		678337 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB4B_HUMAN (8-215): 5.16e-87: 257: 57.94
+	Hs
		838617 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB2A_HUMAN (8-195): 6.73e-96: 280: 62.77
+	Mm
		838709 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (1-215): 1.44e-87: 258: 42.33
+	Hs
		678343 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (1-213): 8.5e-86: 254: 45.54
+	Hs
		678359 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11B_HUMAN (1-215): 1.84e-84: 251: 44.65
+	Hs
		678394 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (4-215): 8.23e-84: 249: 40.57
+	Hs
		678377 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2B_HUMAN (8-215): 1.34e-81: 244: 55.14
+	Hs
		838621 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB14_HUMAN (1-215): 3.21e-90: 265: 100.00
+	Hs
		591772 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77
+	Hs
		838625 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (1-215): 1.44e-87: 258: 42.33
+	Hs
		838624 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (1-213): 8.5e-86: 254: 45.54
+	Hs
		838647 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11B_HUMAN (1-215): 1.84e-84: 251: 44.65
+	Hs
		838683 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1B_HUMAN (4-215): 8.23e-84: 249: 40.57
+	Hs
		838669 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB2B_HUMAN (8-215): 1.34e-81: 244: 55.14
+	Dm
		1197044 Q9VLB7_DROME (1-440): 0: 657: 67.80		Q86BK8_DROME (1-215): 2.42e-85: 254: 81.40
+	Dm
		185708 Q9VLB7_DROME (1-440): 0: 657: 67.80		O18335_DROME (1-213): 2.61e-83: 248: 45.07
+	Dm
		185501 Q9VLB7_DROME (1-440): 0: 657: 67.80		O18332_DROME (1-214): 2.19e-82: 245: 39.25