HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: RAB31 (Q13636)
Ras-related protein Rab-31 (Ras-related protein Rab-22B)
Gene: RAB31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 195
+	Hs
		592123 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5A_HUMAN (4-195): 4.32e-93: 271: 45.92
+	Hs
		678330 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5C_HUMAN (4-195): 2.12e-92: 270: 45.92
+	Hs
		678339 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5B_HUMAN (2-195): 2.32e-91: 267: 44.44
+	Hs
		678408 GDIA_HUMAN (1-447): 0: 724: 100.00		RB22A_HUMAN (2-195): 1.19e-90: 264: 71.13
+	Hs
		678344 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1A_HUMAN (7-195): 5.95e-87: 256: 38.14
+	Mm
		838709 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (7-195): 5.95e-87: 256: 38.14
+	Hs
		678359 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11B_HUMAN (7-195): 1.07e-85: 253: 35.29
+	Hs
		678394 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (7-195): 3.69e-86: 253: 36.79
+	Hs
		592161 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5A_HUMAN (4-195): 4.32e-93: 271: 45.92
+	Hs
		838605 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5C_HUMAN (4-195): 2.12e-92: 270: 45.92
+	Hs
		678340 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB10_HUMAN (7-195): 8.83e-83: 245: 38.22
+	Hs
		678338 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2A_HUMAN (1-186): 2.7e-82: 244: 36.84
+	Hs
		678343 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (7-195): 7.42e-82: 243: 35.15
+	Hs
		838618 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5B_HUMAN (2-195): 2.32e-91: 267: 44.44
+	Hs
		678377 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2B_HUMAN (1-195): 1.49e-81: 242: 32.41
+	Hs
		838625 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (7-195): 5.95e-87: 256: 38.14
+	Hs
		838619 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB10_HUMAN (7-195): 8.83e-83: 245: 38.22
+	Hs
		838617 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB2A_HUMAN (1-186): 2.7e-82: 244: 36.84
+	Hs
		838624 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (7-195): 7.42e-82: 243: 35.15
+	Hs
		838614 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB25_HUMAN (7-167): 5.51e-46: 152: 41.62