HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: Q5W0J0 (Q5W0J0)
small monomeric GTPase (EC 3.6.5.2)
Gene: RAB18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 161
+	Hs
		678397 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB18_HUMAN (1-161): 3.09e-68: 207: 78.16
+	Hs
		678377 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2B_HUMAN (4-154): 6.51e-61: 189: 30.09
+	Hs
		678338 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2A_HUMAN (5-145): 2.89e-60: 187: 32.80
+	Hs
		838690 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB18_HUMAN (1-161): 3.09e-68: 207: 78.16
+	Hs
		678344 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1A_HUMAN (1-155): 1.2e-54: 172: 26.11
+	Mm
		838709 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (1-155): 1.2e-54: 172: 26.11
+	Hs
		678343 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (2-155): 2.78e-53: 169: 24.76
+	Hs
		678394 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (1-155): 1.85e-53: 169: 25.25
+	Hs
		678359 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11B_HUMAN (2-161): 1.31e-52: 167: 26.05
+	Hs
		838669 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB2B_HUMAN (4-154): 6.51e-61: 189: 30.09
+	Hs
		838617 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB2A_HUMAN (5-145): 2.89e-60: 187: 32.80
+	Hs
		838625 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (1-155): 1.2e-54: 172: 26.11
+	Hs
		838624 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (2-155): 2.78e-53: 169: 24.76
+	Hs
		838683 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1B_HUMAN (1-155): 1.85e-53: 169: 25.25
+	Hs
		838647 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11B_HUMAN (2-161): 1.31e-52: 167: 26.05
+	Hs
		678341 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB14_HUMAN (9-126): 1.48e-16: 75.1: 32.32
+	Sp
		568530 GDI1_SCHPO (1-429): 0: 620: 57.91		YPT3_SCHPO (2-158): 4.63e-54: 171: 25.47
+	Hs
		838621 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB14_HUMAN (9-126): 1.48e-16: 75.1: 32.32
+	Dm
		1369984 Q9VLB7_DROME (1-440): 0: 657: 67.80		Q9W4A0_DROME (9-158): 4.46e-29: 107: 37.25
+	Dm
		1369964 Q9VLB7_DROME (1-440): 0: 657: 67.80		Q9VM50_DROME (3-125): 7.58e-18: 78.6: 29.76