HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: RB22A (Q9UL26)
Ras-related protein Rab-22A (Rab-22)
Gene: RAB22A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.80	0.779

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 194
+	Hs
		678330 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5C_HUMAN (5-194): 8.52e-88: 258: 47.94
+	Hs
		678351 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB31_HUMAN (1-194): 5.57e-87: 255: 71.13
+	Hs
		592123 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5A_HUMAN (5-194): 4.31e-85: 251: 47.94
+	Hs
		678339 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5B_HUMAN (5-194): 9.06e-85: 251: 47.94
+	Hs
		678344 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1A_HUMAN (6-194): 2.29e-83: 246: 36.60
+	Hs
		678394 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (6-194): 5.61e-83: 245: 36.27
+	Mm
		838709 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (6-194): 2.29e-83: 246: 36.60
+	Hs
		678343 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (1-194): 1.99e-79: 237: 35.21
+	Hs
		678340 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB10_HUMAN (1-194): 1.97e-79: 236: 34.00
+	Hs
		838605 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5C_HUMAN (5-194): 8.52e-88: 258: 47.94
+	Hs
		838635 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB31_HUMAN (1-194): 5.57e-87: 255: 71.13
+	Hs
		592161 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5A_HUMAN (5-194): 4.31e-85: 251: 47.94
+	Hs
		838618 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5B_HUMAN (5-194): 9.06e-85: 251: 47.94
+	Hs
		838625 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (6-194): 2.29e-83: 246: 36.60
+	Hs
		838683 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1B_HUMAN (6-194): 5.61e-83: 245: 36.27
+	Hs
		838699 GDIB_HUMAN (1-444): 0: 700: 86.49		RB22A_HUMAN (1-194): 9.31e-82: 242: 100.00
+	Hs
		838624 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (1-194): 1.99e-79: 237: 35.21
+	Hs
		838619 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB10_HUMAN (1-194): 1.97e-79: 236: 34.00
+	Dm
		185501 Q9VLB7_DROME (1-440): 0: 657: 67.80		O18332_DROME (6-194): 4.91e-82: 243: 34.54
+	Dm
		1358727 Q9VLB7_DROME (1-440): 0: 657: 67.80		RAB5_DROME (5-194): 1.79e-59: 186: 46.11