HitPredict

Interactor 1: S10A7 (P31151)
Protein S100-A7 (Psoriasin) (S100 calcium-binding protein A7)
Gene: S100A7

Interactor 2: PAK5 (Q9P286)
Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)
Gene: PAK5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 101 Hs			1 719
+	Hs
		416529 S10A9_HUMAN (4-101): 4.09e-28: 99: 23.53		PAK5_HUMAN (1-719): 0: 673: 100.00
+	Hs
		678496 S10A7_HUMAN (1-101): 8.48e-31: 106: 100.00		M3K3_HUMAN (76-699): 1.76e-147: 445: 21.05
+	Hs
		396789 S10A8_HUMAN (2-94): 6.39e-23: 86.1: 22.92		M3K3_HUMAN (76-699): 1.76e-147: 445: 21.05
+	Hs
		682050 CRNN_HUMAN (2-101): 1.5e-27: 105: 21.36		AKT1_HUMAN (307-716): 1.36e-131: 399: 19.77
+	Hs
		707403 S10A3_HUMAN (2-98): 1.12e-25: 93.4: 16.51		AKT3_HUMAN (308-716): 4.79e-132: 400: 19.39
+	Hs
		681685 S10A3_HUMAN (2-98): 1.12e-25: 93.4: 16.51		AKT1_HUMAN (307-716): 1.36e-131: 399: 19.77
+	Hs
		678444 S10A7_HUMAN (1-101): 8.48e-31: 106: 100.00		STK4_HUMAN (426-717): 2.11e-120: 370: 37.42
+	Hs
		682028 S10AE_HUMAN (4-84): 2.54e-18: 74.9: 21.69		AKT1_HUMAN (307-716): 1.36e-131: 399: 19.77
+	Hs
		639135 S100P_HUMAN (4-93): 5.29e-30: 104: 26.88		STK24_HUMAN (416-717): 5.17e-118: 363: 36.18
+	Hs
		639107 S100P_HUMAN (4-93): 5.29e-30: 104: 26.88		STK26_HUMAN (441-717): 8.59e-116: 356: 36.56
+	Hs
		596271 FILA_HUMAN (4-101): 4.51e-20: 85: 21.78		STK4_HUMAN (426-717): 2.11e-120: 370: 37.42
+	Hs
		615217 S10A1_HUMAN (2-94): 1.3e-30: 105: 19.79		KS6A1_HUMAN (386-714): 2.98e-109: 349: 22.03
+	Hs
		638962 S100P_HUMAN (4-93): 5.29e-30: 104: 26.88		KS6A1_HUMAN (386-714): 2.98e-109: 349: 22.03
+	Hs
		416736 S10A6_HUMAN (2-92): 4.58e-23: 86.5: 23.40		STK24_HUMAN (416-717): 5.17e-118: 363: 36.18
+	Hs
		661265 S10A2_HUMAN (1-92): 3.45e-28: 99.6: 22.11		KS6A1_HUMAN (386-714): 2.98e-109: 349: 22.03
+	Hs
		642947 S10A4_HUMAN (2-92): 2.19e-27: 97.7: 23.40		KS6A1_HUMAN (386-714): 2.98e-109: 349: 22.03
+	Hs
		416717 S10A6_HUMAN (2-92): 4.58e-23: 86.5: 23.40		STK26_HUMAN (441-717): 8.59e-116: 356: 36.56
+	Hs
		380782 S100B_HUMAN (4-93): 2.11e-25: 92.3: 24.73		KS6A1_HUMAN (386-714): 2.98e-109: 349: 22.03
+	Hs
		416623 S10A6_HUMAN (2-92): 4.58e-23: 86.5: 23.40		KS6A1_HUMAN (386-714): 2.98e-109: 349: 22.03