HitPredict

Interactor 1: MK04 (P31152)
Mitogen-activated protein kinase 4 (MAP kinase 4) (MAPK 4) (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK)
Gene: MAPK4

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 587 Hs			1 543
+	Hs
		678541 MK04_HUMAN (1-587): 0: 530: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		678540 MK04_HUMAN (1-587): 0: 530: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573140 MK04_HUMAN (1-587): 0: 530: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		1085489 MK06_HUMAN (1-586): 3.18e-135: 412: 52.72		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		625579 CDK2_HUMAN (17-318): 7.7e-138: 404: 31.27		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826682 MK06_HUMAN (1-586): 3.18e-135: 412: 52.72		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Rn
		88992 MK03_RAT (11-361): 2.92e-135: 401: 39.83		D4AC23_RAT (1-543): 0: 583: 88.97
+	Hs
		625228 CDK2_HUMAN (17-318): 7.7e-138: 404: 31.27		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Rn
		600467 MK03_RAT (11-361): 2.92e-135: 401: 39.83		TCPG_RAT (1-541): 0: 576: 31.09
+	Hs
		821229 MK06_HUMAN (1-586): 3.18e-135: 412: 52.72		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		625220 CDK2_HUMAN (17-318): 7.7e-138: 404: 31.27		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573281 MK06_HUMAN (1-586): 3.18e-135: 412: 52.72		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Rn
		600455 MK03_RAT (11-361): 2.92e-135: 401: 39.83		TCPE_RAT (3-527): 0: 550: 29.59
+	Hs
		573132 CDK2_HUMAN (17-318): 7.7e-138: 404: 31.27		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Rn
		600336 MK03_RAT (11-361): 2.92e-135: 401: 39.83		TCPA_RAT (2-533): 0: 542: 34.36
+	Rn
		600476 MK03_RAT (11-361): 2.92e-135: 401: 39.83		TCPD_RAT (14-520): 0: 537: 32.95
+	Hs
		678543 MK04_HUMAN (1-587): 0: 530: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Sc
		691051 HOG1_YEAST (14-328): 2.36e-61: 211: 37.54		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		843216 MK06_HUMAN (1-586): 3.18e-135: 412: 52.72		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		625246 CDK2_HUMAN (17-318): 7.7e-138: 404: 31.27		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79