HitPredict

Interactor 1: RAD16 (P31244)
DNA repair protein RAD16 (EC 3.6.4.-) (ATP-dependent helicase RAD16)
Gene: RAD16

Interactor 2: MSH6 (Q03834)
DNA mismatch repair protein MSH6 (MutS protein homolog 6) (Postmeiotic segregation protein 3)
Gene: MSH6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 790 Sc			1 1242
+	Hs
		855558 CHD8_HUMAN (75-788): 1.42e-171: 549: 22.16		MSH6_HUMAN (60-1198): 0: 1045: 28.78
+	Hs
		855551 SMRCD_HUMAN (7-790): 7.29e-155: 479: 19.60		MSH6_HUMAN (60-1198): 0: 1045: 28.78
+	Sp
		194167 FFT3_SCHPO (166-774): 3.49e-142: 443: 24.29		MSH6_SCHPO (74-1202): 0: 1056: 39.74
+	Hs
		594213 SMRCD_HUMAN (7-790): 7.29e-155: 479: 19.60		MSH3_HUMAN (164-1176): 0: 884: 23.37
+	Hs
		794312 SMRCD_HUMAN (7-790): 7.29e-155: 479: 19.60		MSH2_HUMAN (298-1193): 0: 838: 22.07
+	Hs
		794255 HLTF_HUMAN (99-787): 2.02e-147: 460: 24.73		MSH2_HUMAN (298-1193): 0: 838: 22.07
+	Hs
		855463 CHD3_HUMAN (367-790): 4.85e-63: 232: 18.42		MSH6_HUMAN (60-1198): 0: 1045: 28.78
+	Sp
		194191 FFT3_SCHPO (166-774): 3.49e-142: 443: 24.29		MSH2_SCHPO (313-1205): 0: 714: 22.88
+	Sc
		639252 FUN30_YEAST (177-776): 2.25e-137: 436: 22.82		MSH2_YEAST (314-1209): 0: 713: 20.59
+	Sc
		639260 RAD5_YEAST (200-788): 1.56e-64: 236: 28.16		MSH2_YEAST (314-1209): 0: 713: 20.59