HitPredict

Interactor 1: HXA10 (P31260)
Homeobox protein Hox-A10 (Homeobox protein Hox-1.8) (Homeobox protein Hox-1H) (PL)
Gene: HOXA10

Interactor 2: MK14 (Q16539)
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
Gene: MAPK14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 360
+	Hs
		1082645 HXC10_HUMAN (39-410): 7.11e-38: 141: 36.46		MK14_HUMAN (1-360): 8.56e-158: 448: 100.00
+	Hs
		679001 HXC9_HUMAN (175-385): 4.62e-35: 132: 35.84		MK14_HUMAN (1-360): 8.56e-158: 448: 100.00
+	Hs
		567846 HXB9_HUMAN (158-398): 1.07e-29: 117: 31.54		MK14_HUMAN (1-360): 8.56e-158: 448: 100.00
+	Hs
		568021 HXB6_HUMAN (188-405): 3.68e-28: 112: 28.31		MK14_HUMAN (1-360): 8.56e-158: 448: 100.00
+	Hs
		595605 HXA5_HUMAN (151-408): 4.51e-26: 107: 24.35		MK14_HUMAN (1-360): 8.56e-158: 448: 100.00
+	Hs
		800950 HXC10_HUMAN (39-410): 7.11e-38: 141: 36.46		MK09_HUMAN (8-348): 7.79e-115: 341: 50.14