Interactor 1: SUH (P31266)
Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa)
Gene: Rbpj
Interactor 2: NOTC1 (Q01705)
Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: Notch1
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.88 | 1.00 | 0.942 |
The method score is based on:
Property | Details |
---|---|
Experiments | 17526737, 17210915, 11518718, 8749394, 18832173, 22258620 |
Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Ank_2~BTD, Ank_2~LAG1-DNAbind, Ank_2~TIG_SUH |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001837 - epithelial to mesenchymal transition GO:0001947 - heart looping GO:0002193 - MAML1-RBP-Jkappa- ICN1 complex and 37 others more... |
Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024