Interactor 1: SUH (P31266)
Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa)
Gene: Rbpj

Interactor 2: NOTC3 (Q61982)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: Notch3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11518718
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~BTD, Ank_2~LAG1-DNAbind, Ank_2~TIG_SUH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005654 - nucleoplasm
GO:0007219 - Notch signaling pathway
GO:0030182 - neuron differentiation
GO:0045596 - negative regulation of cell differentiation
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 526
Mm

1 2318
+ Mm
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Mm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024