HitPredict

Interactor 1: HXA9 (P31269)
Homeobox protein Hox-A9 (Homeobox protein Hox-1G)
Gene: HOXA9

Interactor 2: KMT2A (Q03164)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15960974, 22174154
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0009952 - anterior/posterior pattern specification GO:0060216 - definitive hemopoiesis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 3969
+	Hs
		678902 HXC8_HUMAN (95-267): 1.34e-38: 136: 34.09		KMT2A_HUMAN (1-3969): 0: 3187: 100.00
+	Hs
		829859 HXA1_HUMAN (34-267): 3.76e-32: 122: 25.21		EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54
+	Hs
		595604 HXA5_HUMAN (7-271): 8.29e-31: 117: 24.28		EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54
+	Hs
		203641 HXA1_HUMAN (34-267): 3.76e-32: 122: 25.21		SUV91_HUMAN (3630-3968): 1.07e-83: 284: 18.97
+	Ce
		880558 HM09_CAEEL (188-271): 4.89e-31: 114: 35.71		DPFF1_CAEEL (1206-1543): 4.23e-65: 229: 16.80
+	Hs
		882142 GSC_HUMAN (65-266): 8.77e-29: 111: 18.23		KMT2C_HUMAN (384-1407): 6.81e-11: 71.4: 10.23
+	Hs
		152620 GSC_HUMAN (65-266): 8.77e-29: 111: 18.23		KMT2D_HUMAN (11-1393): 8.17e-09: 64.4: 10.47