HitPredict

Interactor 1: HXC8 (P31273)
Homeobox protein Hox-C8 (Homeobox protein Hox-3A)
Gene: HOXC8

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 242 Hs			1 217
+	Hs
		557620 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		337365 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46
+	Hs
		412045 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		522809 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		411952 HXB5_HUMAN (1-216): 2.62e-33: 123: 25.67		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		412088 MEOX2_HUMAN (28-223): 3.49e-32: 121: 26.24		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		433220 HXB5_HUMAN (1-216): 2.62e-33: 123: 25.67		YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91
+	Hs
		433532 HXB5_HUMAN (1-216): 2.62e-33: 123: 25.67		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Hs
		447219 HXB5_HUMAN (1-216): 2.62e-33: 123: 25.67		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		433531 HXC4_HUMAN (1-241): 9.8e-31: 116: 22.27		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Hs
		412044 HXA9_HUMAN (145-219): 1.17e-19: 87: 66.67		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58