HitPredict

Interactor 1: HXC8 (P31273)
Homeobox protein Hox-C8 (Homeobox protein Hox-3A)
Gene: HOXC8

Interactor 2: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.50	0.607

Property	Details
Experiments	32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 242 Hs			1 824
+	Hs
		678959 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		ANS1A_HUMAN (215-809): 4.34e-51: 196: 13.93
+	Hs
		678925 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		Q49AR9_HUMAN (515-809): 7.44e-41: 160: 18.86
+	Hs
		678929 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		ARH_HUMAN (660-809): 3.74e-40: 152: 18.42
+	Hs
		838173 MEOX2_HUMAN (28-223): 3.49e-32: 121: 26.24		ANS1A_HUMAN (215-809): 4.34e-51: 196: 13.93
+	Hs
		829957 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		ANS1A_HUMAN (215-809): 4.34e-51: 196: 13.93
+	Hs
		526808 HXD8_HUMAN (1-238): 2.94e-40: 141: 52.96		ARH_HUMAN (660-809): 3.74e-40: 152: 18.42
+	Hs
		829874 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		Q49AR9_HUMAN (515-809): 7.44e-41: 160: 18.86
+	Hs
		678986 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		JIP1_HUMAN (13-351): 1.71e-16: 86: 18.75
+	Hs
		67830 NOTO_HUMAN (11-240): 1.53e-31: 118: 17.67		ARH_HUMAN (660-809): 3.74e-40: 152: 18.42
+	Hs
		257571 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77
+	Hs
		678932 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		TENS2_HUMAN (105-502): 5.26e-10: 65.4: 17.16
+	Hs
		257551 HXB7_HUMAN (1-220): 6.8e-41: 141: 35.40		ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77
+	Hs
		257549 HXD4_HUMAN (1-242): 4.91e-38: 135: 26.98		ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77
+	Hs
		257570 HXA7_HUMAN (2-220): 7.25e-38: 133: 38.12		ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77
+	Hs
		257560 HXB6_HUMAN (1-226): 5.11e-33: 121: 34.04		ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77
+	Hs
		679137 TLX1_HUMAN (72-242): 2.51e-31: 119: 21.05		KMT2C_HUMAN (99-499): 1.88e-11: 70.5: 11.38
+	Hs
		882142 GSC_HUMAN (7-242): 3.52e-32: 119: 15.42		KMT2C_HUMAN (99-499): 1.88e-11: 70.5: 11.38
+	Hs
		201848 HXA2_HUMAN (35-219): 7.72e-31: 118: 24.12		SYNJ1_HUMAN (305-673): 3.46e-11: 69.4: 9.49
+	Hs
		257562 HXA5_HUMAN (1-221): 1.53e-31: 118: 29.21		ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77
+	Hs
		829896 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		TENS2_HUMAN (105-502): 5.26e-10: 65.4: 17.16