HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: TFAM (Q00059)
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)
Gene: TFAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 246
+	Hs
		679177 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61
+	Hs
		213389 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61
+	Dm
		950017 UBX_DROME (65-265): 4.1e-33: 128: 23.83		Q86BR8_DROME (47-232): 1.39e-29: 113: 30.16
+	Hs
		174010 SHOX_HUMAN (185-299): 6.57e-34: 127: 25.22		SOX6_HUMAN (49-160): 2.17e-25: 106: 12.82
+	Dm
		950090 UBX_DROME (65-265): 4.1e-33: 128: 23.83		Q9VUD3_DROME (144-228): 1.27e-24: 103: 20.23
+	Hs
		174009 SHOX_HUMAN (185-299): 6.57e-34: 127: 25.22		SOX5_HUMAN (49-150): 1.14e-23: 101: 12.75
+	Mm
		590253 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		SOX5_MOUSE (49-150): 1.99e-23: 100: 12.75
+	Dm
		115538 UBX_DROME (65-265): 4.1e-33: 128: 23.83		M9PFG6_DROME (123-232): 2.76e-23: 99.1: 14.91
+	Dm
		114548 UBX_DROME (65-265): 4.1e-33: 128: 23.83		M9PCZ7_DROME (147-224): 1.88e-22: 97.5: 25.61
+	Mm
		590306 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		SOX14_MOUSE (150-235): 1.26e-23: 97.1: 22.22
+	Mm
		590352 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		SOX17_MOUSE (117-233): 1.62e-22: 96.7: 14.88
+	Mm
		590259 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		SOX15_MOUSE (135-242): 1.96e-20: 88.3: 18.75
+	Hs
		1334459 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		SOX21_HUMAN (153-234): 2.41e-13: 69.8: 22.09
+	Mm
		93370 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		E9Q0B9_MOUSE (151-230): 1.48e-16: 80.2: 19.05
+	Hs
		643330 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		HMGB2_HUMAN (48-142): 4.13e-15: 73.3: 16.84
+	Hs
		449682 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69
+	Hs
		968024 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		SOX21_HUMAN (153-234): 2.41e-13: 69.8: 22.09
+	Mm
		590313 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		SSRP1_MOUSE (118-219): 1.25e-11: 66: 26.42
+	Dm
		950103 UBX_DROME (65-265): 4.1e-33: 128: 23.83		Q9W2K8_DROME (46-188): 2.63e-10: 61.7: 23.08
+	Mm
		590425 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		TOX4_MOUSE (151-222): 3.34e-09: 58.7: 21.05