HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: ARI1B (Q8NFD5)
AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R)
Gene: ARID1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 2319
+	Hs
		213359 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		ARI1B_HUMAN (21-2319): 0: 845: 100.00
+	Hs
		1244304 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		ARI1B_HUMAN (21-2319): 0: 845: 100.00
+	Hs
		967923 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		ARI1B_HUMAN (21-2319): 0: 845: 100.00
+	Hs
		679135 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI3B_HUMAN (973-1383): 5.54e-63: 228: 20.53
+	Hs
		679162 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI3A_HUMAN (970-1310): 2.43e-51: 194: 21.88
+	Hs
		1218101 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		ARI3B_HUMAN (973-1383): 5.54e-63: 228: 20.53
+	Hs
		213373 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		ARI3A_HUMAN (970-1310): 2.43e-51: 194: 21.88
+	Hs
		1306893 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		ARI3A_HUMAN (970-1310): 2.43e-51: 194: 21.88
+	Mm
		590545 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		ARI3B_MOUSE (963-1383): 1.75e-55: 206: 20.99
+	Hs
		679114 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI4B_HUMAN (1141-1230): 6.03e-24: 113: 29.03
+	Dm
		950077 UBX_DROME (65-265): 4.1e-33: 128: 23.83		KDM5_DROME (943-1317): 8.03e-37: 155: 18.28
+	Hs
		146163 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		679182 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		CHD7_HUMAN (1174-1670): 1.92e-11: 72.1: 9.96
+	Hs
		679137 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		KMT2C_HUMAN (598-1634): 5.9e-09: 64: 11.53
+	Mm
		57759 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		ARI1A_MOUSE (33-1422): 3.42e-18: 94.6: 8.98
+	Hs
		146119 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		213398 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		CHD7_HUMAN (1174-1670): 1.92e-11: 72.1: 9.96
+	Hs
		213358 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		KMT2C_HUMAN (598-1634): 5.9e-09: 64: 11.53
+	Hs
		967993 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		CHD7_HUMAN (1174-1670): 1.92e-11: 72.1: 9.96
+	Mm
		590420 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		KMT2C_MOUSE (798-1666): 2.29e-09: 65.6: 10.82