Interactor 1: PO3F3 (P31361)
POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1) (Octamer-binding protein 8) (Oct-8) (Octamer-binding transcription factor 8) (OTF-8)
Gene: Pou3f3

Interactor 2: SOX8 (Q04886)
Transcription factor SOX-8
Gene: SOX8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16582099
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~Pou
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 497
Mm

1 464
+ Hs
+ Mm
+ Ce
+ Dm
+ Mm
+ Mm
+ Dm
+ Mm
+ Mm
+ Ce
+ Mm
+ Hs
+ Mm
+ Mm
+ Dm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024