Interactor 1: CCR4 (P31384)
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4 (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase) (Glucose-repressible alcohol dehydrogenase transcriptional effector)
Gene: CCR4

Interactor 2: POP2 (P39008)
Poly(A) ribonuclease POP2 (EC 3.1.13.4) (CCR4-associated factor 1)
Gene: POP2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 7791755, 11113136, 9463387, 10490603, 11733989, 16715093, 11805826, 11805837, 9311989, 11239395, 16554755, 16429126, 18719252, 37968396, 22959269, 14759368, 14734555, 12215412, 9504907, 19107399 and 1 others

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Identification Methods coimmunoprecipitation, two hybrid, biochemical, pull down, molecular sieving, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0004535 - poly(A)-specific ribonuclease activity
and 6 others

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Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 837
Sc

1 433
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Dm
+ Sp
+ Ce
+ Ce

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Last updated: 15 Jul 2024