Interactor 1: VATC (P31412)
V-type proton ATPase subunit C (V-ATPase subunit C) (V-ATPase 42 kDa subunit) (Vacuolar proton pump subunit C)
Gene: VMA5

Interactor 2: VPP1 (P32563)
V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)
Gene: VPH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 11592965, 19081055, 37968396, 22367203, 23071676, 24805887
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, unspecified method, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_C~V_ATPase_I
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
GO:1902600 - proton transmembrane transport
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 392
Sc

1 840
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024