Interactor 1: GBRA5 (P31644)
Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5) (GABAAR subunit alpha-5)
Gene: GABRA5

Interactor 2: GBRA3 (P34903)
Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3) (GABAAR subunit alpha-3)
Gene: GABRA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0004890 - GABA-A receptor activity
GO:0005237 - inhibitory extracellular ligand-gated monoatomic ion channel activity
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007214 - gamma-aminobutyric acid signaling pathway
and 13 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 462
Hs

1 492
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024