HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	25184681, 26831064, 22990118
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 1863
+	Hs
		749711 DNJA4_HUMAN (1-397): 1.01e-159: 456: 73.37		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		243320 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		749766 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		636262 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		749923 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		1243266 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		MCPH1_HUMAN (1150-1857): 1.33e-95: 331: 14.19
+	Hs
		1290899 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		TRI11_HUMAN (11-390): 3.9e-74: 257: 11.49