HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	26561776, 31685992
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 403
+	Hs
		243351 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		PTEN_HUMAN (1-403): 4.63e-168: 478: 100.00
+	Hs
		890794 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		PTEN_HUMAN (1-403): 4.63e-168: 478: 100.00
+	Hs
		161594 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		GAK_HUMAN (22-402): 1.74e-116: 370: 23.39
+	Hs
		1167751 DNJB4_HUMAN (5-349): 1.73e-125: 367: 32.77		TPTE2_HUMAN (1-347): 4.78e-106: 324: 34.72
+	Hs
		279317 DNJB5_HUMAN (5-347): 8.97e-125: 365: 35.21		TPTE2_HUMAN (1-347): 4.78e-106: 324: 34.72
+	Hs
		636293 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		TPTE_HUMAN (1-347): 1.17e-102: 316: 33.61
+	Sc
		633459 MAS5_YEAST (1-396): 8.35e-140: 406: 45.37		TEP1_YEAST (3-190): 1.01e-46: 167: 24.17
+	Sc
		633484 MAS5_YEAST (1-396): 8.35e-140: 406: 45.37		CDC14_YEAST (17-189): 2.5e-38: 146: 22.70