HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: MTA70 (Q86U44)
N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70)
Gene: METTL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	29507755, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0007283 - spermatogenesis
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 580
+	Hs
		243479 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		MTA70_HUMAN (1-580): 0: 990: 100.00
+	Hs
		1199108 DNJB4_HUMAN (5-349): 1.73e-125: 367: 32.77		MTA70_HUMAN (1-580): 0: 990: 100.00
+	Hs
		636368 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		MTA70_HUMAN (1-580): 0: 990: 100.00
+	Hs
		681609 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		MET14_HUMAN (365-575): 1.44e-82: 267: 29.44
+	Hs
		243621 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		MET14_HUMAN (365-575): 1.44e-82: 267: 29.44
+	Hs
		1336044 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		MET14_HUMAN (365-575): 1.44e-82: 267: 29.44