HitPredict

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 539
+	Hs
		681738 AKT1_HUMAN (1-480): 0: 586: 100.00		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		681999 AKT1_HUMAN (1-480): 0: 586: 100.00		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		681735 AKT1_HUMAN (1-480): 0: 586: 100.00		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Dm
		1213398 AKT1_DROME (3-474): 0: 523: 60.37		Q9VHL2_DROME (20-538): 0: 554: 32.64
+	Dm
		1213403 AKT1_DROME (3-474): 0: 523: 60.37		Q9VK69_DROME (5-538): 0: 548: 68.22
+	Hs
		843420 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		843394 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		568593 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		826928 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		826897 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		1306721 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		1306691 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		821449 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		821419 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		568585 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		843210 KS6A1_HUMAN (85-407): 6.15e-92: 296: 26.39		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		821353 SGK3_HUMAN (149-447): 5.26e-100: 310: 51.00		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Dm
		1180659 AKT1_DROME (3-474): 0: 523: 60.37		Q7KKI0_DROME (27-535): 3.34e-94: 299: 37.17