HitPredict

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: H2B3B (Q8N257)
Histone H2B type 3-B (H2B type 12) (H2B-clustered histone 26) (H2B.U histone 1)
Gene: H2BC26

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 480 Hs			1 126
+	Mm
		682111 AKT1_MOUSE (1-480): 0: 587: 98.33		H2B2B_MOUSE (1-126): 1.97e-55: 170: 95.24
+	Hs
		617926 AKT1_HUMAN (1-480): 0: 586: 100.00		H2B1O_HUMAN (1-126): 2.99e-55: 170: 96.83
+	Mm
		682113 AKT1_MOUSE (1-480): 0: 587: 98.33		H2B1C_MOUSE (1-126): 1.76e-54: 168: 95.24
+	Hs
		420806 AKT1_HUMAN (1-480): 0: 586: 100.00		H2B1J_HUMAN (1-126): 1.17e-54: 168: 95.24
+	Hs
		681686 AKT1_HUMAN (1-480): 0: 586: 100.00		H2B1B_HUMAN (1-126): 1.92e-54: 168: 96.03
+	Hs
		681878 AKT1_HUMAN (1-480): 0: 586: 100.00		H2B2E_HUMAN (1-126): 9.44e-55: 168: 96.03
+	Hs
		617927 AKT2_HUMAN (1-477): 0: 559: 81.21		H2B1O_HUMAN (1-126): 2.99e-55: 170: 96.83
+	Hs
		420807 AKT2_HUMAN (1-477): 0: 559: 81.21		H2B1J_HUMAN (1-126): 1.17e-54: 168: 95.24
+	Hs
		682137 AKT2_HUMAN (1-477): 0: 559: 81.21		H2B1B_HUMAN (1-126): 1.92e-54: 168: 96.03
+	Hs
		682181 AKT2_HUMAN (1-477): 0: 559: 81.21		H2B2E_HUMAN (1-126): 9.44e-55: 168: 96.03
+	Hs
		682194 AKT2_HUMAN (1-477): 0: 559: 81.21		H2B3B_HUMAN (1-126): 1.04e-52: 163: 100.00
+	Hs
		408666 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B1M_HUMAN (1-126): 5.4e-55: 169: 92.86
+	Hs
		241418 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B1K_HUMAN (1-126): 2.01e-54: 168: 94.44
+	Hs
		408525 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B1J_HUMAN (1-126): 1.17e-54: 168: 95.24
+	Hs
		408565 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B1B_HUMAN (1-126): 1.92e-54: 168: 96.03
+	Hs
		408583 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2BFS_HUMAN (1-126): 1.84e-54: 168: 92.86
+	Hs
		408591 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B1C_HUMAN (1-126): 1.76e-54: 168: 95.24
+	Hs
		408624 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B2E_HUMAN (1-126): 9.44e-55: 168: 96.03
+	Hs
		408585 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B1D_HUMAN (1-126): 4.1e-54: 167: 95.24
+	Hs
		408664 KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67		H2B1N_HUMAN (1-126): 3.84e-54: 167: 96.03