HitPredict

Interactor 1: AKT2 (P31751)
RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC protein kinase beta) (RAC-PK-beta)
Gene: AKT2

Interactor 2: DP13A (Q9UKG1)
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)
Gene: APPL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 10490823, 17030088, 15070827
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BAR_3~PH, PH~PH, PH~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
and 2 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 481
Hs

1 709
+ Hs
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+ Mm
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Last updated: 15 Jul 2024