HitPredict

Interactor 1: HECA2 (A8MVW5)
HEPACAM family member 2 (Mitotic kinetics regulator)
Gene: HEPACAM2

Interactor 2: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ig_3~fn3, Ig_3~I-set, Ig_3~Ig_3
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 1948
+	Hs
		685236 CEAM8_HUMAN (14-366): 4.75e-62: 207: 23.10		PTPRS_HUMAN (1-1948): 0: 1690: 100.00
+	Hs
		1031992 CEA21_HUMAN (89-237): 1.08e-42: 154: 28.86		PTPRS_HUMAN (1-1948): 0: 1690: 100.00
+	Hs
		68222 HECA2_HUMAN (1-462): 2.38e-97: 302: 100.00		PTPRF_HUMAN (1-1948): 0: 1528: 65.42
+	Hs
		489970 CEA21_HUMAN (89-237): 1.08e-42: 154: 28.86		PTPRF_HUMAN (1-1948): 0: 1528: 65.42
+	Mm
		530202 NCAM1_MOUSE (22-461): 2.22e-61: 218: 14.19		PTPRA_MOUSE (1168-1948): 0: 802: 37.59
+	Gg
		47583 CNTN1_CHICK (120-461): 1.01e-34: 140: 12.57		A0A8V0YWD3_CHICK (1185-1948): 0: 822: 40.57
+	Hs
		685250 CEAM8_HUMAN (14-366): 4.75e-62: 207: 23.10		SDK2_HUMAN (3-1422): 1.73e-122: 432: 16.47
+	Hs
		1108780 CEA21_HUMAN (89-237): 1.08e-42: 154: 28.86		SDK2_HUMAN (3-1422): 1.73e-122: 432: 16.47
+	Mm
		1186724 PTK7_MOUSE (150-422): 4.03e-29: 123: 16.25		Q7TQG5_MOUSE (3-931): 2.65e-106: 377: 19.98
+	Hs
		441175 CD22_HUMAN (38-437): 2.92e-30: 126: 15.71		PTPRC_HUMAN (450-1662): 1.43e-85: 311: 15.29
+	Hs
		1264775 TITIN_HUMAN (57-461): 3.78e-09: 61.5: 10.27		NEO1_HUMAN (322-1447): 6.5e-95: 341: 13.80
+	Hs
		617163 CNTN1_HUMAN (121-461): 1.2e-35: 142: 15.03		PTPRZ_HUMAN (1387-1668): 4.97e-47: 189: 27.21
+	Hs
		616914 CNTN1_HUMAN (121-461): 1.2e-35: 142: 15.03		PTPRB_HUMAN (257-1309): 2.07e-37: 157: 12.51
+	Hs
		685244 CEAM8_HUMAN (14-366): 4.75e-62: 207: 23.10		PTPRK_HUMAN (113-670): 1.42e-10: 68.9: 15.72
+	Hs
		1069962 LRIG1_HUMAN (121-434): 1.8e-39: 154: 13.51		PTPRK_HUMAN (113-670): 1.42e-10: 68.9: 15.72
+	Hs
		1069952 PXDN_HUMAN (2-261): 5.14e-39: 152: 17.91		PTPRK_HUMAN (113-670): 1.42e-10: 68.9: 15.72