Interactor 1: MP2K1 (P31938)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: Map2k1
Interactor 2: DJC27 (Q8CFP6)
DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein)
Gene: Dnajc27
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24746703 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DnaJ~Pkinase, Pkinase~Ras |
| Common GO terms | GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005770 - late endosome GO:0070374 - positive regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
