HitPredict

Interactor 1: HNRH1 (P31943)
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene: HNRNPH1

Interactor 2: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.755

Property	Details
Experiments	9111328, 32960270
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 156
+	Hs
		853881 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00
+	Hs
		516425 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00
+	Hs
		516495 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Hs
		516339 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Hs
		1020249 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11
+	Hs
		516484 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11
+	Hs
		1031344 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Hs
		516689 PABP3_HUMAN (1-446): 8.68e-79: 258: 12.42		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Mm
		665745 PABP1_MOUSE (1-446): 3.46e-84: 272: 13.70		TIA1_MOUSE (1-140): 7e-21: 89.1: 19.58
+	Hs
		516471 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		TIAR_HUMAN (1-155): 1e-19: 85.7: 16.46
+	Hs
		1031490 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		PUF60_HUMAN (30-113): 1.88e-17: 80.1: 30.95
+	Hs
		516730 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		PUF60_HUMAN (30-113): 1.88e-17: 80.1: 30.95
+	Hs
		682825 HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Mm
		936558 HNRH2_MOUSE (1-449): 2.44e-72: 236: 95.77		ELAV1_MOUSE (7-125): 1.85e-24: 98: 19.01
+	Mm
		193432 HNRH1_MOUSE (1-449): 1.88e-75: 244: 99.78		TIA1_MOUSE (1-140): 7e-21: 89.1: 19.58
+	Hs
		682823 HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86
+	Hs
		1020275 ESRP1_HUMAN (26-385): 1.46e-42: 161: 20.29		ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11
+	Hs
		474021 PAB4L_HUMAN (3-188): 3.01e-38: 144: 15.03		PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18
+	Hs
		474019 PAB4L_HUMAN (3-188): 3.01e-38: 144: 15.03		ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11