HitPredict

Interactor 1: HNRH1 (P31943)
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene: HNRNPH1

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	9111328, 35271311, 32960270
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 790
+	Hs
		998037 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		516479 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		855029 HNRPF_HUMAN (253-438): 2.66e-11: 67.3: 26.06		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		682587 HNRH3_HUMAN (10-86): 1.84e-10: 64.1: 32.47		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		582252 NUCL_HUMAN (75-373): 1.19e-09: 62.5: 18.89		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Sc
		376713 PABP_YEAST (104-380): 3.85e-35: 139: 14.84		NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53