HitPredict

Interactor 1: HNRH1 (P31943)
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene: HNRNPH1

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26318153, 35271311, 17643375
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006396 - RNA processing and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 355
+	Hs
		516511 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		162035 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		161948 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		516663 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		516424 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		161970 HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		516495 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		516339 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		516358 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		609726 HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		453331 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		453107 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		474021 PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92		PAB4L_HUMAN (179-259): 1.74e-16: 81.7: 18.29
+	Hs
		516689 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		PABP3_HUMAN (172-267): 5.97e-16: 80.9: 16.50
+	Mm
		665745 PABP1_MOUSE (1-446): 3.46e-84: 272: 13.70		TIA1_MOUSE (176-270): 8.88e-14: 73.6: 18.75
+	Hs
		516471 PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70		TIAR_HUMAN (174-269): 2.98e-13: 72.1: 16.50
+	Hs
		453174 HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Mm
		193432 HNRH1_MOUSE (1-449): 1.88e-75: 244: 99.78		TIA1_MOUSE (176-270): 8.88e-14: 73.6: 18.75