HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 156
+	Hs
		790736 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00
+	Hs
		909455 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		910162 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59
+	Hs
		883468 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68
+	Hs
		683234 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68
+	Hs
		910023 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68
+	Hs
		60315 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55
+	Hs
		683708 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68
+	Hs
		60300 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55
+	Hs
		257595 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25
+	Hs
		257572 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25
+	Hs
		909789 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANKH1_HUMAN (68-155): 3.32e-18: 82.3: 19.32
+	Hs
		909924 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANR27_HUMAN (2-85): 2.82e-15: 73.8: 21.59
+	Hs
		909999 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00
+	Hs
		683691 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00
+	Hs
		910104 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Hs
		683767 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Mm
		56841 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		TANC2_MOUSE (1-99): 3.54e-10: 59.3: 21.57
+	Hs
		910048 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TANC2_HUMAN (1-99): 3.54e-10: 59.3: 21.57
+	Hs
		683730 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		TANC2_HUMAN (1-99): 3.54e-10: 59.3: 21.57