HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 342
+	Hs
		902864 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		902866 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		909485 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		902860 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		902884 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Xl
		223342 O57468_XENLA (4-243): 2.71e-143: 402: 66.12		RBP4A_XENLA (2-294): 7.57e-45: 160: 15.21
+	Hs
		683930 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		927391 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Ce
		785020 14331_CAEEL (1-244): 4.43e-109: 316: 76.61		LIN53_CAEEL (10-342): 2.97e-67: 218: 14.88
+	Xl
		292751 Q8AVW5_XENLA (3-244): 9.01e-129: 365: 84.30		RBP4A_XENLA (2-294): 7.57e-45: 160: 15.21
+	Hs
		684063 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		903106 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		792954 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		683188 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		792963 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		792950 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		792974 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82