HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: FOXK1 (P85037)
Forkhead box protein K1 (Myocyte nuclear factor) (MNF)
Gene: FOXK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	17353931, 33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 733
+	Hs
		909439 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		FOXK1_HUMAN (1-733): 1.15e-97: 319: 100.00
+	Hs
		926921 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		FOXK1_HUMAN (1-733): 1.15e-97: 319: 100.00
+	Hs
		646796 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		FOXK1_HUMAN (1-733): 1.15e-97: 319: 100.00
+	Hs
		206820 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		FOXO3_HUMAN (250-678): 4.49e-61: 219: 19.09
+	Hs
		206807 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FOXO3_HUMAN (250-678): 4.49e-61: 219: 19.09
+	Hs
		206822 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		FOXO3_HUMAN (250-678): 4.49e-61: 219: 19.09
+	Hs
		909490 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		FOXO1_HUMAN (257-708): 1.43e-47: 181: 16.25
+	Hs
		683300 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FOXO1_HUMAN (257-708): 1.43e-47: 181: 16.25
+	Hs
		206799 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		FOXO3_HUMAN (250-678): 4.49e-61: 219: 19.09
+	Hs
		926976 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		FOXO1_HUMAN (257-708): 1.43e-47: 181: 16.25
+	Hs
		909499 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		FOXC1_HUMAN (234-616): 6.29e-45: 171: 19.85
+	Hs
		683226 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FOXA1_HUMAN (242-592): 2.55e-44: 167: 19.11
+	Hs
		68644 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FOXO6_HUMAN (219-616): 3.02e-35: 142: 18.07
+	Hs
		646840 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		FOXO1_HUMAN (257-708): 1.43e-47: 181: 16.25
+	Hs
		206819 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		FOXO3_HUMAN (250-678): 4.49e-61: 219: 19.09
+	Hs
		68643 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		FOXO6_HUMAN (219-616): 3.02e-35: 142: 18.07
+	Hs
		297821 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		K0754_HUMAN (6-323): 7.74e-09: 61.7: 14.99
+	Hs
		297815 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		K0754_HUMAN (6-323): 7.74e-09: 61.7: 14.99
+	Hs
		297824 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (6-323): 7.74e-09: 61.7: 14.99
+	Hs
		68646 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		FOXO6_HUMAN (219-616): 3.02e-35: 142: 18.07