HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: BORG5 (Q00587)
Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)
Gene: CDC42EP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	36931259, 24255178
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 391
+	Hs
		909450 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		926926 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		646802 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		904448 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		960617 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Mm
		935599 1433F_MOUSE (4-244): 8.67e-108: 312: 75.51		BORG5_MOUSE (1-391): 2.17e-155: 445: 68.51
+	Hs
		683967 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		982489 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54