HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	33961781, 36931259, 24255178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1202
+	Hs
		909508 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		926994 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Mm
		926835 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		LIPA2_MOUSE (35-1202): 5.01e-134: 442: 62.90
+	Hs
		909824 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		LIPB2_HUMAN (434-1149): 2.41e-95: 327: 18.61
+	Hs
		522602 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH7_HUMAN (153-902): 1.92e-36: 152: 13.40
+	Mm
		926855 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH9_MOUSE (10-824): 1.34e-29: 130: 11.24
+	Hs
		728460 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH11_HUMAN (209-847): 1.2e-22: 107: 12.15
+	Hs
		724761 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		728466 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH11_HUMAN (209-847): 1.2e-22: 107: 12.15
+	Hs
		502907 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH3_HUMAN (1-547): 1.77e-21: 104: 13.20
+	Mm
		926886 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MY18A_MOUSE (6-434): 4.44e-19: 96: 12.76
+	Hs
		909488 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CGNL1_HUMAN (10-379): 5.91e-14: 79.1: 14.67
+	Hs
		683298 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		CGNL1_HUMAN (10-379): 5.91e-14: 79.1: 14.67
+	Hs
		926974 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		CGNL1_HUMAN (10-379): 5.91e-14: 79.1: 14.67
+	Mm
		890551 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		LIPA3_MOUSE (1-265): 2.85e-12: 73.6: 12.45
+	Hs
		725130 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		909765 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		683512 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Mm
		926804 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH10_MOUSE (320-813): 7.13e-10: 66: 10.91
+	Hs
		927253 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62