HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: KCC2B (Q13554)
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)
Gene: CAMK2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12619878
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 666
+	Hs
		909916 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MARK4_HUMAN (1-569): 2.18e-140: 429: 23.76
+	Mm
		910308 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		MARK4_MOUSE (1-569): 5.54e-140: 428: 24.09
+	Xl
		223345 O57468_XENLA (4-243): 2.71e-143: 402: 66.12		Q8QGV3_XENLA (1-587): 3.66e-140: 430: 24.50
+	Hs
		909730 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MARK2_HUMAN (2-579): 4.63e-139: 427: 24.96
+	At
		965291 14332_ARATH (1-241): 4.75e-145: 407: 63.27		CDPK1_ARATH (6-386): 1.31e-140: 425: 31.51
+	Hs
		683485 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MARK2_HUMAN (2-579): 4.63e-139: 427: 24.96
+	Mm
		910234 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		MARK2_MOUSE (2-573): 9.16e-139: 426: 25.38
+	Xl
		223344 O57468_XENLA (4-243): 2.71e-143: 402: 66.12		Q804T2_XENLA (1-595): 2.77e-139: 426: 22.20
+	Hs
		647862 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MARK3_HUMAN (1-552): 5.75e-138: 423: 24.49
+	Hs
		647835 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MARK3_HUMAN (1-552): 5.75e-138: 423: 24.49
+	Hs
		159186 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CSKP_HUMAN (10-308): 1.66e-81: 278: 46.73
+	Hs
		909531 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KCC2G_HUMAN (381-666): 5.77e-58: 206: 50.00
+	Hs
		683326 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KCC2G_HUMAN (381-666): 5.77e-58: 206: 50.00
+	Mm
		659446 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		KCC2B_MOUSE (436-666): 3.97e-59: 209: 60.94
+	Mm
		926866 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		KCC2G_MOUSE (469-666): 2.29e-58: 207: 65.15
+	Hs
		909532 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KCC2D_HUMAN (507-666): 1.24e-53: 193: 71.25
+	Mm
		926819 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		KCC2D_MOUSE (507-666): 1.24e-53: 193: 71.25
+	Hs
		910174 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KCC2A_HUMAN (493-663): 1.13e-50: 184: 61.40
+	Hs
		683826 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KCC2A_HUMAN (493-663): 1.13e-50: 184: 61.40
+	Mm
		515221 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		KCC2A_MOUSE (493-663): 1.7e-50: 184: 61.40