HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20363754
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007165 - signal transduction GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 550
+	Hs
		909544 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12
+	Hs
		683333 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12
+	Mm
		82753 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		B9EKJ1_MOUSE (213-549): 9.53e-34: 139: 14.12
+	Hs
		927025 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12
+	Mm
		82777 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		B9EKJ1_MOUSE (213-549): 9.53e-34: 139: 14.12
+	Mm
		910262 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DBNL_MOUSE (335-550): 1.4e-31: 128: 29.46
+	Hs
		927483 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PACN1_HUMAN (241-549): 2.37e-31: 128: 16.86
+	Hs
		927459 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SH3G1_HUMAN (365-549): 6.52e-31: 125: 17.01
+	Hs
		910088 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ABI2_HUMAN (396-547): 4.11e-13: 73.7: 29.68
+	Hs
		683599 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		STAM1_HUMAN (416-546): 2.82e-13: 74.4: 21.83
+	Hs
		683758 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ABI2_HUMAN (396-547): 4.11e-13: 73.7: 29.68
+	Mm
		910242 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SRBS2_MOUSE (452-549): 1.51e-11: 69.6: 22.00
+	Hs
		298967 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91
+	Hs
		299007 V9HW98_HUMAN (3-243): 4.39e-144: 405: 65.43		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91
+	Hs
		298952 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91
+	Hs
		927585 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ABI2_HUMAN (396-547): 4.11e-13: 73.7: 29.68
+	Hs
		298968 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91
+	Hs
		904543 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12
+	Hs
		298950 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91
+	Hs
		298965 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91