HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SRGP1 (Q7Z6B7)
SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)
Gene: SRGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	33961781, 35271311, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1085
+	Hs
		909743 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRGP1_HUMAN (1-1085): 0: 805: 100.00
+	Mm
		910322 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SRGP2_MOUSE (1-1085): 0: 695: 65.52
+	Hs
		253335 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRGP2_HUMAN (1-1085): 0: 691: 65.49
+	Hs
		253321 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SRGP2_HUMAN (1-1085): 0: 691: 65.49
+	Mm
		910285 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SRGP3_MOUSE (1-1085): 0: 685: 67.30
+	Hs
		909873 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		HMHA1_HUMAN (30-844): 4.17e-90: 315: 14.60
+	Hs
		70666 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYO9A_HUMAN (75-970): 5.98e-86: 308: 11.93
+	Hs
		70650 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MYO9A_HUMAN (75-970): 5.98e-86: 308: 11.93
+	Hs
		64684 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RHG32_HUMAN (456-1077): 4.76e-84: 302: 17.03
+	Hs
		683775 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RHG23_HUMAN (377-1036): 1.33e-84: 303: 17.34
+	Hs
		64662 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RHG32_HUMAN (456-1077): 4.76e-84: 302: 17.03
+	Hs
		302638 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		FA13A_HUMAN (494-1085): 4.89e-85: 299: 16.05
+	Hs
		302635 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FA13A_HUMAN (494-1085): 4.89e-85: 299: 16.05
+	Mm
		910284 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		RHG33_MOUSE (346-1043): 2.15e-82: 295: 17.21
+	Hs
		909650 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RHG21_HUMAN (251-1044): 1.44e-78: 285: 16.73
+	Hs
		683416 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RHG21_HUMAN (251-1044): 1.44e-78: 285: 16.73
+	Hs
		910011 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RGAP1_HUMAN (132-777): 1.31e-81: 281: 13.92
+	Hs
		683698 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RGAP1_HUMAN (132-777): 1.31e-81: 281: 13.92
+	Hs
		506563 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		BCR_HUMAN (494-673): 1.21e-17: 90.9: 30.56
+	Hs
		506525 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		BCR_HUMAN (494-673): 1.21e-17: 90.9: 30.56