HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	36931259, 24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 888
+	Hs
		909744 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SH3R1_HUMAN (1-888): 1.17e-136: 431: 100.00
+	Hs
		909712 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		OTOG_HUMAN (355-783): 3.08e-49: 192: 17.27
+	Hs
		683472 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		OTOG_HUMAN (355-783): 3.08e-49: 192: 17.27
+	Hs
		683599 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		STAM1_HUMAN (420-699): 2.16e-25: 113: 12.84
+	Mm
		910242 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SRBS2_MOUSE (428-502): 1.42e-22: 106: 44.32
+	Hs
		298967 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		299007 V9HW98_HUMAN (3-243): 4.39e-144: 405: 65.43		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		298952 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		298968 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		909551 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ARHG7_HUMAN (725-888): 1.36e-14: 80.3: 19.88
+	Hs
		909979 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRBS1_HUMAN (125-416): 3.54e-14: 79.3: 19.54
+	Hs
		683678 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SRBS1_HUMAN (125-416): 3.54e-14: 79.3: 19.54
+	Hs
		909634 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SH319_HUMAN (133-192): 4.35e-13: 75.4: 40.00
+	Hs
		683401 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SH319_HUMAN (133-192): 4.35e-13: 75.4: 40.00
+	Hs
		275184 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		GRAP2_HUMAN (835-887): 3.61e-12: 70.6: 28.30
+	Mm
		926883 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		ARHG7_MOUSE (800-888): 2.17e-13: 76.4: 26.97
+	Hs
		909706 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DNMBP_HUMAN (4-190): 5.38e-11: 68.9: 15.10
+	Hs
		683469 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DNMBP_HUMAN (4-190): 5.38e-11: 68.9: 15.10
+	Hs
		909849 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SH3R3_HUMAN (691-888): 1.88e-10: 66.8: 20.71
+	Hs
		683567 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SH3R3_HUMAN (691-888): 1.88e-10: 66.8: 20.71