HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: HOME1 (Q86YM7)
Homer protein homolog 1 (Homer-1)
Gene: HOMER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 354
+	Mm
		910353 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		HOME1_MOUSE (1-354): 2.36e-58: 194: 95.36
+	Mm
		910327 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		HOME3_MOUSE (3-354): 1.54e-57: 192: 47.44
+	Mm
		926900 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		HOME1_MOUSE (1-354): 2.36e-58: 194: 95.36
+	Mm
		926869 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		HOME3_MOUSE (3-354): 1.54e-57: 192: 47.44
+	Mm
		926781 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		ENAH_MOUSE (1-155): 1.58e-37: 145: 26.06
+	Hs
		840451 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		VASP_HUMAN (1-146): 3.19e-28: 115: 22.36
+	Mm
		910250 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		GRDN_MOUSE (158-347): 3.89e-27: 115: 22.80
+	Hs
		909625 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		GRDN_HUMAN (158-347): 6.51e-26: 111: 22.28
+	Hs
		683394 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		GRDN_HUMAN (158-347): 6.51e-26: 111: 22.28
+	Mm
		926795 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		GRDN_MOUSE (158-347): 3.89e-27: 115: 22.80
+	Hs
		840453 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		VASP_HUMAN (1-146): 3.19e-28: 115: 22.36
+	Mm
		926774 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		EVL_MOUSE (1-153): 1.5e-27: 113: 21.52
+	Hs
		910111 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DAPLE_HUMAN (148-347): 2.64e-14: 76.5: 19.70
+	Hs
		683774 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DAPLE_HUMAN (148-347): 2.64e-14: 76.5: 19.70
+	Mm
		93548 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DESP_MOUSE (105-347): 9.87e-12: 68.5: 15.48
+	Hs
		909845 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DLG5_HUMAN (107-349): 5.1e-10: 63.1: 13.81
+	Hs
		683563 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DLG5_HUMAN (107-349): 5.1e-10: 63.1: 13.81
+	Hs
		909658 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MRCKA_HUMAN (67-345): 9.31e-09: 59.3: 12.63
+	Hs
		683425 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MRCKA_HUMAN (67-345): 9.31e-09: 59.3: 12.63
+	Hs
		551660 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DESP_HUMAN (95-342): 9.29e-09: 59.3: 12.30