HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: DOCK7 (Q96N67)
Dedicator of cytokinesis protein 7
Gene: DOCK7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 2140
+	Hs
		909920 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Hs
		927415 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Mm
		56981 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		A2A9M5_MOUSE (1-2140): 0: 2746: 97.52
+	Mm
		56982 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		A2A9M5_MOUSE (1-2140): 0: 2746: 97.52
+	Hs
		647195 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Hs
		904999 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Mm
		910297 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DOCK8_MOUSE (2-2139): 0: 2478: 55.64
+	Hs
		683533 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DOCK4_HUMAN (342-862): 8.54e-68: 257: 17.93
+	Hs
		909993 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DOCK9_HUMAN (2-279): 3.87e-49: 196: 22.41
+	Hs
		683685 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DOCK9_HUMAN (2-279): 3.87e-49: 196: 22.41
+	Hs
		927490 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DOCK9_HUMAN (2-279): 3.87e-49: 196: 22.41
+	Hs
		909638 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75
+	Hs
		683403 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75
+	Hs
		63199 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		A6NIW2_HUMAN (1-212): 1.48e-44: 181: 26.75
+	Hs
		927120 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75
+	Hs
		904844 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		DOCK4_HUMAN (342-862): 8.54e-68: 257: 17.93
+	Hs
		646953 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75
+	Hs
		108780 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		H0Y572_HUMAN (1354-1496): 2.45e-27: 110: 15.39
+	Hs
		905077 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		DOCK9_HUMAN (2-279): 3.87e-49: 196: 22.41
+	Hs
		904658 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75