HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1343
+	Hs
		909931 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		99940 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Mm
		99950 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		909664 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		683429 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		927150 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		910133 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		683798 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		683194 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		909576 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		GAPD1_HUMAN (412-1051): 3.01e-122: 417: 13.70
+	Hs
		683356 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		GAPD1_HUMAN (412-1051): 3.01e-122: 417: 13.70
+	Hs
		809256 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		927058 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		GAPD1_HUMAN (412-1051): 3.01e-122: 417: 13.70
+	Hs
		909774 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RASL3_HUMAN (182-865): 4.68e-111: 376: 35.91
+	Hs
		927262 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RASL3_HUMAN (182-865): 4.68e-111: 376: 35.91
+	Hs
		598455 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		598433 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Mm
		910233 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		NF1_MOUSE (408-712): 4.15e-82: 300: 23.51
+	Hs
		598458 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Mm
		926782 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		NF1_MOUSE (408-712): 4.15e-82: 300: 23.51