HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: AGAP2 (Q99490)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (GTP-binding and GTPase-activating protein 2) (GGAP2) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30833542
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1192
+	Hs
		91531 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E7EUN2_HUMAN (111-1160): 0: 793: 43.10
+	Hs
		91530 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		E7EUN2_HUMAN (111-1160): 0: 793: 43.10
+	Hs
		910161 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		AGAP1_HUMAN (387-1160): 0: 729: 54.02
+	Hs
		683815 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		AGAP1_HUMAN (387-1160): 0: 729: 54.02
+	Hs
		927661 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		AGAP1_HUMAN (387-1160): 0: 729: 54.02
+	Hs
		91532 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		E7EUN2_HUMAN (111-1160): 0: 793: 43.10
+	Hs
		647382 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		AGAP1_HUMAN (387-1160): 0: 729: 54.02
+	Hs
		909925 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		AGAP3_HUMAN (387-1167): 0: 676: 51.59
+	Hs
		683633 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		AGAP3_HUMAN (387-1167): 0: 676: 51.59
+	Hs
		909866 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ARAP2_HUMAN (579-1113): 2.68e-83: 301: 19.96
+	Hs
		683584 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ARAP2_HUMAN (579-1113): 2.68e-83: 301: 19.96
+	Hs
		927353 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ARAP2_HUMAN (579-1113): 2.68e-83: 301: 19.96
+	Hs
		647152 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		ARAP2_HUMAN (579-1113): 2.68e-83: 301: 19.96
+	Mm
		910346 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		GIT2_MOUSE (938-1145): 2.91e-72: 257: 32.43
+	Mm
		910271 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		GIT1_MOUSE (938-1145): 1.93e-71: 256: 32.88
+	Mm
		926813 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		GIT1_MOUSE (938-1145): 1.93e-71: 256: 32.88
+	Hs
		904575 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		ACAP1_HUMAN (759-1181): 6.46e-88: 302: 20.40
+	Hs
		904928 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		ARAP2_HUMAN (579-1113): 2.68e-83: 301: 19.96
+	Hs
		904553 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		GIT2_HUMAN (938-1145): 5.51e-73: 260: 31.98
+	Hs
		909582 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ACAP2_HUMAN (646-1181): 8.39e-43: 170: 14.00