HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: ARHG4 (Q9NR80)
Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor 1) (Asef) (Asef1)
Gene: ARHGEF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 690
+	Hs
		910068 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ARHG4_HUMAN (1-690): 0: 547: 100.00
+	Hs
		927568 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ARHG4_HUMAN (1-690): 0: 547: 100.00
+	Hs
		647309 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		ARHG4_HUMAN (1-690): 0: 547: 100.00
+	Hs
		909921 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SPT13_HUMAN (95-690): 1.64e-140: 427: 57.24
+	Hs
		683631 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SPT13_HUMAN (95-690): 1.64e-140: 427: 57.24
+	Hs
		927416 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SPT13_HUMAN (95-690): 1.64e-140: 427: 57.24
+	Hs
		647196 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		SPT13_HUMAN (95-690): 1.64e-140: 427: 57.24
+	Hs
		909717 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		FGD6_HUMAN (88-662): 2.71e-74: 263: 15.33
+	Mm
		926851 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		ARHG6_MOUSE (146-687): 3.48e-79: 269: 19.71
+	Hs
		683475 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FGD6_HUMAN (88-662): 2.71e-74: 263: 15.33
+	Hs
		909781 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ARHGJ_HUMAN (3-632): 1.86e-75: 260: 14.64
+	Hs
		927201 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		FGD6_HUMAN (88-662): 2.71e-74: 263: 15.33
+	Hs
		647028 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		FGD6_HUMAN (88-662): 2.71e-74: 263: 15.33
+	Hs
		50576 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PKHG3_HUMAN (288-556): 2.6e-31: 133: 34.44
+	Hs
		50560 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PKHG3_HUMAN (288-556): 2.6e-31: 133: 34.44
+	Hs
		50581 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PKHG3_HUMAN (288-556): 2.6e-31: 133: 34.44
+	Hs
		50558 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		PKHG3_HUMAN (288-556): 2.6e-31: 133: 34.44
+	Hs
		909551 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ARHG7_HUMAN (15-84): 2.51e-09: 62.7: 9.59
+	Mm
		926883 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		ARHG7_MOUSE (15-84): 4.99e-09: 61.6: 8.22
+	Mm
		1321772 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		ARHG7_MOUSE (15-84): 4.99e-09: 61.6: 8.22