HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	36931259, 17353931
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 2610
+	Hs
		910149 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		927651 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Mm
		808343 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		NEDD4_MOUSE (2258-2608): 9.66e-121: 407: 19.89
+	Rn
		910358 1433E_RAT (3-243): 4.39e-144: 405: 65.43		NEDD4_RAT (2258-2608): 4.01e-119: 403: 20.11
+	Mm
		93264 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		E9PXB7_MOUSE (2255-2608): 3.94e-119: 401: 21.67
+	Hs
		909930 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		683637 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Mm
		808372 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		NEDD4_MOUSE (2258-2608): 9.66e-121: 407: 19.89
+	Mm
		910302 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		NED4L_MOUSE (2255-2608): 2.21e-116: 398: 21.67
+	Rn
		716563 1433B_RAT (1-246): 3.55e-141: 397: 98.37		NEDD4_RAT (2258-2608): 4.01e-119: 403: 20.11
+	Hs
		927423 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Mm
		93281 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		E9PXB7_MOUSE (2255-2608): 3.94e-119: 401: 21.67
+	Hs
		125318 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125351 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		909564 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		683347 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		927043 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		909468 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	Hs
		926955 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	At
		788566 14333_ARATH (3-241): 4.44e-143: 402: 62.96		UPL2_ARATH (2424-2604): 7.84e-20: 100: 34.60